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Ionotropic glutamate receptor that functions being a cation permeable ligand-gated ion channel, gated by L-glutamate as well as glutamatergic agonist kainic acid. L-glutamate functions as an excitatory neurotransmitter at numerous synapses within the central anxious program. Binding on the excitatory neurotransmitter L-glutamate induces a conformat